Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation

<p>Abstract</p> <p>Background</p> <p>Acromegaly, an orphan disease usually caused by a benign pituitary tumour, is characterised by hyper-secretion of growth hormone (GH) and insulin-like growth factor I (IGF-1). It is associated with reduced life expectancy, cardiovasc...

Full description

Bibliographic Details
Main Authors: Connock Martin J, Adi Yaser, Moore David J, Bayliss Sue
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Endocrine Disorders
Online Access:http://www.biomedcentral.com/1472-6823/9/20