ROS Regulate Cardiac Function via a Distinct Paracrine Mechanism

Reactive oxygen species (ROS) can act cell autonomously and in a paracrine manner by diffusing into nearby cells. Here, we reveal a ROS-mediated paracrine signaling mechanism that does not require entry of ROS into target cells. We found that under physiological conditions, nonmyocytic pericardial c...

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Bibliographic Details
Main Authors: Hui-Ying Lim, Weidong Wang, Jianming Chen, Karen Ocorr, Rolf Bodmer
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714001430