Cerebral Apolipoprotein D Exits the Brain and Accumulates in Peripheral Tissues

Cerebral Apolipoprotein D Exits the Brain and Accumulates in Peripheral Tissues

Apolipoprotein D (ApoD) is a secreted lipocalin associated with neuroprotection and lipid metabolism. In rodent, the bulk of its expression occurs in the central nervous system. Despite this, ApoD has profound effects in peripheral tissues, indicating that neural ApoD may reach peripheral organs. We...

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Bibliographic Details
Main Authors: Frederik Desmarais, Vincent Hervé, Karl F. Bergeron, Gaétan Ravaut, Morgane Perrotte, Guillaume Fyfe-Desmarais, Eric Rassart, Charles Ramassamy, Catherine Mounier
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
apolipoprotein D
basigin
protein accumulation
blood-brain barrier
Online Access:https://www.mdpi.com/1422-0067/22/8/4118

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