Ventilation-induced changes correlate to pulmonary vascular response and VEGF, VEGFR-1/2, and eNOS expression in the rat model of postnatal hypoxia

Ventilation-induced changes correlate to pulmonary vascular response and VEGF, VEGFR-1/2, and eNOS expression in the rat model of postnatal hypoxia

Neonatal asphyxia occurs due to reduction in oxygen supply to vital organs in the newborn. Rapid restoration of oxygen to the lungs after a long period of asphyxia can cause lung injury and decline of respiratory function, which result from the activity of molecules that induce vascular changes in t...

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Bibliographic Details
Main Authors: R.L. Figueira, F.L. Gonçalves, A.R. Prado, M.C. Ribeiro, K.M. Costa, O. Castro e Silva, L. Sbragia
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Neonatal hypoxia
Mechanical ventilation
VEGF
VEGF receptors
eNOS enzyme
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001100608&lng=en&tlng=en

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