False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians

Schwannoma is a rare source of false-positive 18F-fluorodeoxyglucose (18F-FDG) uptake in Positron-emission tomography (PET/CT), inducing potential errors in staging of several solid cancer, with implications for patient management. This clinical case reports the situation of a patient undergoing an...

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Main Authors: Paul Boré, Renaud Descourt, Luc Ollivier, Pierre-Yves Le Roux, Ronan Abgral
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00275/full
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spelling doaj-665bd09023d44d51bf21b229912d32e22020-11-25T01:05:27ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2018-10-01510.3389/fmed.2018.00275415934False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting PhysiciansPaul Boré0Renaud Descourt1Luc Ollivier2Pierre-Yves Le Roux3Ronan Abgral4Service d'Oncologie Médicale, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, FranceService d'Oncologie Médicale, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, FranceService de Radiothérapie, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, FranceService de Médecine Nucléaire, EA 3878 (GETBO) IF 148, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, FranceService de Médecine Nucléaire, EA 3878 (GETBO) IF 148, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, FranceSchwannoma is a rare source of false-positive 18F-fluorodeoxyglucose (18F-FDG) uptake in Positron-emission tomography (PET/CT), inducing potential errors in staging of several solid cancer, with implications for patient management. This clinical case reports the situation of a patient undergoing an 18F-FDG-PET/CT for initial staging of an ovarian adenocarcinoma. We found a high paramediastinal hypermetabolic mass suspicious of remote extension or secondary synchronous primitive tumor. The biopsy finally reveals a histopathology of Schwannoma, allowing the patient to be eligible for a surgical procedure of her ovarian adenocarcinoma by rejecting the hypothesis of malignancy.https://www.frontiersin.org/article/10.3389/fmed.2018.00275/fullpositron-emission tomographyschwannomaneoplasm stagingovarian neoplasmsmediastinal neoplasms
collection DOAJ
language English
format Article
sources DOAJ
author Paul Boré
Renaud Descourt
Luc Ollivier
Pierre-Yves Le Roux
Ronan Abgral
spellingShingle Paul Boré
Renaud Descourt
Luc Ollivier
Pierre-Yves Le Roux
Ronan Abgral
False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians
Frontiers in Medicine
positron-emission tomography
schwannoma
neoplasm staging
ovarian neoplasms
mediastinal neoplasms
author_facet Paul Boré
Renaud Descourt
Luc Ollivier
Pierre-Yves Le Roux
Ronan Abgral
author_sort Paul Boré
title False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians
title_short False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians
title_full False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians
title_fullStr False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians
title_full_unstemmed False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma—A Caution for Reporting Physicians
title_sort false positive 18f-fdg positron emission tomography findings in schwannoma—a caution for reporting physicians
publisher Frontiers Media S.A.
series Frontiers in Medicine
issn 2296-858X
publishDate 2018-10-01
description Schwannoma is a rare source of false-positive 18F-fluorodeoxyglucose (18F-FDG) uptake in Positron-emission tomography (PET/CT), inducing potential errors in staging of several solid cancer, with implications for patient management. This clinical case reports the situation of a patient undergoing an 18F-FDG-PET/CT for initial staging of an ovarian adenocarcinoma. We found a high paramediastinal hypermetabolic mass suspicious of remote extension or secondary synchronous primitive tumor. The biopsy finally reveals a histopathology of Schwannoma, allowing the patient to be eligible for a surgical procedure of her ovarian adenocarcinoma by rejecting the hypothesis of malignancy.
topic positron-emission tomography
schwannoma
neoplasm staging
ovarian neoplasms
mediastinal neoplasms
url https://www.frontiersin.org/article/10.3389/fmed.2018.00275/full
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