In Vivo Direct Molecular Imaging of Early Tumorigenesis and Malignant Progression Induced by Transgenic Expression of GFP-Met

In Vivo Direct Molecular Imaging of Early Tumorigenesis and Malignant Progression Induced by Transgenic Expression of GFP-Met

The tyrosine kinase receptor Met and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), play an important role in normal developmental processes, as well as in tumorigenicity and metastasis. We constructed a green fluorescent protein (GFP) Met chimeric molecule that functions similarly t...

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Bibliographic Details
Main Authors: Sharon Moshitch-Moshkovitz, Galia Tsarfaty, Dafna W. Kaufman, Gideon Y. Stein, Keren Shichrur, Eddy Solomon, Robert H. Sigler, James H. Resau, George F. Vande Woude, Ilan Tsarfaty
Format: Article
Language:English
Published: Elsevier 2006-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Receptor tyrosine kinase
Met hepatocyte growth factor/scatter factor
sebaceous gland tumor
confocal intravital molecular imaging
GFP transgenic mice
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800552

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