N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo

N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo

Gastric cancer is the most common malignant tumor of the digestive tract and is great challenge in clinical treatment. N6-(2-Hydroxyethyl)-adenosine (HEA), widely present in various fungi, is a natural adenosine derivative with many biological and pharmacological activities. Here, we assessed the an...

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Bibliographic Details
Main Authors: Hongqing Xie, Xiaotong Li, Weiwei Yang, Liping Yu, Xiasen Jiang, Yajie Chen, Zhangfei Shen, Conghui Li, Meier Gu, Liangen Shi
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
N6-(2-Hydroxyethyl)-adenosine
apoptosis
endoplasmic reticulum stress
gastric carcinoma
autophagy
Online Access:https://www.mdpi.com/1422-0067/21/16/5815

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