Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma
An age of 70-year-old man was incidentally found two focal high 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) uptake in the descending colon and in the sigmoid colon. We observed the feature of these two areas in the preplanned 4′-[methyl-11C]-thiothymidine (4DST) positron emission tomography (PET)/compute...
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doaj-66434349af1140359be78bb35bfb28b52021-09-25T23:59:19ZengMDPI AGDiagnostics2075-44182021-09-01111658165810.3390/diagnostics11091658Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and AdenomaRyogo Minamimoto0Hisako Endo1Division of Nuclear Medicine, Department of Radiology, National Center for Global Health and Medicine, Tokyo 1628655, JapanDepartment of Clinical Pathology, Edogawa Hospital, Tokyo 1330052, JapanAn age of 70-year-old man was incidentally found two focal high 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) uptake in the descending colon and in the sigmoid colon. We observed the feature of these two areas in the preplanned 4′-[methyl-11C]-thiothymidine (4DST) positron emission tomography (PET)/computed Tomography (CT)providing cell proliferation imaging. A mass forming high 4DST uptake in the descending colon and focal moderate 4DST uptake in the sigmoid colon was confirmed, and that were proven pathologically as adenocarcinoma and moderate to severe type tubular adenoma, respectively. This is the first report to present that colorectal adenoma can be visualized by proliferation PET imaging and the degree of uptake may enable discrimination of colorectal adenoma from adenocarcinoma, based on pathological considerations.https://www.mdpi.com/2075-4418/11/9/16584DST PET/CTcolorectal adenomacolorectal adenocarcinomaFDG PET/CTcell proliferation imaging |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ryogo Minamimoto Hisako Endo |
spellingShingle |
Ryogo Minamimoto Hisako Endo Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma Diagnostics 4DST PET/CT colorectal adenoma colorectal adenocarcinoma FDG PET/CT cell proliferation imaging |
author_facet |
Ryogo Minamimoto Hisako Endo |
author_sort |
Ryogo Minamimoto |
title |
Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma |
title_short |
Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma |
title_full |
Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma |
title_fullStr |
Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma |
title_full_unstemmed |
Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma |
title_sort |
cell proliferation pet imaging with 4dst pet/ct in colorectal adenocarcinoma and adenoma |
publisher |
MDPI AG |
series |
Diagnostics |
issn |
2075-4418 |
publishDate |
2021-09-01 |
description |
An age of 70-year-old man was incidentally found two focal high 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) uptake in the descending colon and in the sigmoid colon. We observed the feature of these two areas in the preplanned 4′-[methyl-11C]-thiothymidine (4DST) positron emission tomography (PET)/computed Tomography (CT)providing cell proliferation imaging. A mass forming high 4DST uptake in the descending colon and focal moderate 4DST uptake in the sigmoid colon was confirmed, and that were proven pathologically as adenocarcinoma and moderate to severe type tubular adenoma, respectively. This is the first report to present that colorectal adenoma can be visualized by proliferation PET imaging and the degree of uptake may enable discrimination of colorectal adenoma from adenocarcinoma, based on pathological considerations. |
topic |
4DST PET/CT colorectal adenoma colorectal adenocarcinoma FDG PET/CT cell proliferation imaging |
url |
https://www.mdpi.com/2075-4418/11/9/1658 |
work_keys_str_mv |
AT ryogominamimoto cellproliferationpetimagingwith4dstpetctincolorectaladenocarcinomaandadenoma AT hisakoendo cellproliferationpetimagingwith4dstpetctincolorectaladenocarcinomaandadenoma |
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