Evaluation of Antioxidant Capacity and Synergistic Associations of Quinonemethide Triterpenes and Phenolic Substances from Maytenus ilicifolia (Celastraceae)

• Main Authors: Ian Castro-Gamboa, Vânia Aparecida de Freitas Formenton Macedo dos Santos, Maysa Furlan, Maria Valnice Boldrin Zanoni, Daniela Pereira dos Santos
• Format: Article
• Language: English
• Published: MDPI AG 2010-10-01
• Series: Molecules
• Subjects: antioxidant; high-performance liquid chromatography coupled with electrochemical detection (HPLC-EICD); cyclic voltammetry (CV); quinonemethide; flavonoid
• Online Access: http://www.mdpi.com/1420-3049/15/10/6956/

This work describes the isolation of the secondary metabolites identified as the quinonemethides maytenin (1) and pristimerin (2) from Maytenus ilicifolia extracts obtained from root barks of adult plants and roots of seedlings and their quantification by high performance liquid chromatography coupled to a diode array detector. The electrochemical profiles obtained from cyclic voltammetry and a coulometric detector coupled to high-performance liquid chromatography contributed to the evaluation of their antioxidant capacity. The antioxidant properties of individual components and the crude extracts of the root barks of Maytenus ilicifolia were compared and the possible synergistic associations of quinonemethide triterpenes and phenolic substances were investigated by using rutin as a model phenolic compound.