Predictable properties of fitness landscapes induced by adaptational tradeoffs

Fitness effects of mutations depend on environmental parameters. For example, mutations that increase fitness of bacteria at high antibiotic concentration often decrease fitness in the absence of antibiotic, exemplifying a tradeoff between adaptation to environmental extremes. We develop a mathemati...

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Bibliographic Details
Main Authors: Suman G Das, Susana OL Direito, Bartlomiej Waclaw, Rosalind J Allen, Joachim Krug
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/55155