Why do some T cell receptor cytoplasmic domains associate with the plasma membrane?
Based on studies in model systems it has been proposed that the cytoplasmic domains of T cell receptor signalling subunits that have polybasic motifs associate with the plasma membrane, and that this regulates their phosphorylation. Recent experiments in more physiological systems have confirmed mem...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-02-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00029/full |