Comparison between immunization routes of live attenuated Salmonella Typhimurium strains expressing BCSP31, Omp3b and SOD of Brucella abortus in murine model

Comparison between immunization routes of live attenuated Salmonella Typhimurium strains expressing BCSP31, Omp3b and SOD of Brucella abortus in murine model

Live, attenuated Salmonella Typhimurium vaccine candidate expressing BCSP31, Omp3b and SOD proteins of Brucella abortus was constructed. Thirty BALB/c mice were divided equally into three groups, Group A, were intraperitoneally (IP) inoculated with 100 µl of approximately 1.2 × 106 colony-forming un...

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Bibliographic Details
Main Authors: Won Kyong eKim, Ja Young eMoon, Suk eKim, Jin eHur
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Microbiology
Subjects:
Brucella abortus
Brucellosis
murine model
delivery system
Salmonella mutant
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00550/full

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