The Aquaporin3 Promoter Polymorphism −1431 A/G is Associated with Acute Graft Rejection and Cytomegalovirus Infection in Kidney Recipients Due to Altered Immune Cell Migration

The Aquaporin3 Promoter Polymorphism −1431 A/G is Associated with Acute Graft Rejection and Cytomegalovirus Infection in Kidney Recipients Due to Altered Immune Cell Migration

Major complications after kidney transplantation are graft rejection and cytomegalovirus (CMV) infection, which are related to T-cell function, which depends on aquaporin3 (AQP3) expression. The impact of the AQP3 A(−1431)G promoter polymorphism in kidney transplant recipients was unelucidated and w...

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Bibliographic Details
Main Authors: Katharina Rump, Tim Rahmel, Anna-Maria Rustige, Matthias Unterberg, Hartmuth Nowak, Björn Koos, Peter Schenker, Richard Viebahn, Michael Adamzik, Lars Bergmann
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
AQP3
aquaporin 3
polymorphism
kidney transplantation
AQP3 −1431 A/G
rs3860987
Online Access:https://www.mdpi.com/2073-4409/9/6/1421

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