Behavioral experience induces zif268 expression in mature granule cells but suppresses its expression in immature granule cells
Thousands of neurons are born each day in the dentate gyrus (DG), but many of these cells die before reaching maturity. Both death and survival of adult-born neurons are regulated by neuronal activity in DG. The immediate-early gene (IEG) zif268 is an important mediator of these effects, as its expr...
Main Authors: | Kylie A. Huckleberry, Gary A. Kane, Rita eMathis, Sarah eCook, Jon E. Clutton, Michael R. Drew |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-08-01
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Series: | Frontiers in Systems Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2015.00118/full |
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