Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer

Bone metastases are associated with poor prognosis in patients with breast cancer and limited therapeutic options. Here the authors exploit near-infrared light responsive macrophages for the tumor-selective delivery of oxaliplatin prodrug for chemo-photodynamic therapy of primary and bone metastatic...

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Bibliographic Details
Main Authors: Yanjuan Huang, Zilin Guan, Xiuling Dai, Yifeng Shen, Qin Wei, Lingling Ren, Jingwen Jiang, Zhanghong Xiao, Yali Jiang, Di Liu, Zeqian Huang, Xiaoyu Xu, Yong Luo, Chunshun Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24564-0
Description
Summary:Bone metastases are associated with poor prognosis in patients with breast cancer and limited therapeutic options. Here the authors exploit near-infrared light responsive macrophages for the tumor-selective delivery of oxaliplatin prodrug for chemo-photodynamic therapy of primary and bone metastatic breast cancer.
ISSN:2041-1723