The YoaW signal peptide directs efficient secretion of different heterologous proteins fused to a StrepII-SUMO tag in Bacillus subtilis

The YoaW signal peptide directs efficient secretion of different heterologous proteins fused to a StrepII-SUMO tag in Bacillus subtilis

Abstract Background Heterologous gene expression is well established for various prokaryotic model systems. However, low yield, incorrect folding and instability still impede the production of soluble, bioactive proteins. To improve protein production with the Gram-positive host Bacillus subtilis, a...

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Bibliographic Details
Main Authors: Janine Heinrich, Chris Drewniok, Eva Neugebauer, Harald Kellner, Thomas Wiegert
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Microbial Cell Factories
Subjects:
B. subtilis
SUMO
Secretion
Heterologous expression
Online Access:http://link.springer.com/article/10.1186/s12934-019-1078-0

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http://link.springer.com/article/10.1186/s12934-019-1078-0

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