Investigation of the underlying genes and mechanism of familial hypercholesterolemia through bioinformatics analysis

Investigation of the underlying genes and mechanism of familial hypercholesterolemia through bioinformatics analysis

Abstract Background Familial hypercholesterolemia (FH) is one of the commonest inherited metabolic disorders. Abnormally high level of low-density lipoprotein cholesterol (LDL-C) in blood leads to premature atherosclerosis onset and a high risk of cardiovascular disease (CVD). However, the specific...

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Bibliographic Details
Main Authors: Dinghui Wang, Bin Liu, Tianhua Xiong, Wenlong Yu, Qiang She
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Cardiovascular Disorders
Subjects:
Familial hypercholesterolemia
LDL-C
Atherosclerosis
Bioinformatics analysis
ITGAL
TLN1
Online Access:http://link.springer.com/article/10.1186/s12872-020-01701-z

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