Fluorogenic RNA Aptamers: A Nano-platform for Fabrication of Simple and Combinatorial Logic Gates

RNA aptamers that bind non-fluorescent dyes and activate their fluorescence are highly sensitive, nonperturbing, and convenient probes in the field of synthetic biology. These RNA molecules, referred to as light-up aptamers, operate as molecular nanoswitches that alter folding and fluorescence funct...

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Bibliographic Details
Main Authors: Victoria Goldsworthy, Geneva LaForce, Seth Abels, Emil F. Khisamutdinov
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/8/12/984