The Activation and Signaling Mechanisms of GPR56/ADGRG1 in Melanoma Cell

The Activation and Signaling Mechanisms of GPR56/ADGRG1 in Melanoma Cell

Adhesion G protein-coupled receptors (aGPCRs) constitute the second largest GPCR subfamily. GPR56/ADGRG1 is a member of the ADGRG subgroup of aGPCRs. Although GPR56 is best known for its pivotal role in the cerebral cortical development, it is also important for tumor progression. Numerous studies h...

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Bibliographic Details
Main Authors: Kuan-Yeh Huang, Hsi-Hsien Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Oncology
Subjects:
GPR56
melanoma
tumor progression
signaling pathways
adhesion GPCR
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00304/full

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