Hydrolysis of a novel lysosomotropic enzyme substrate for beta-galactosidase within intact cells.

With the goal of improving the detection of lysosomal sphingolipid hydrolases within intact cells, we have recently synthesized a new fluorophor, O-[4-(1-imidazolyl)butyl]-2,3-dicyano-1,4-hydroquinonyl beta-D-galactopyranoside (Im-DCH-beta-Gal). In the present study, we evaluated the interaction of...

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Bibliographic Details
Main Authors: C R Kaneski, S A French, M R Brescia, M J Harbour, S P Miller
Format: Article
Language:English
Published: Elsevier 1994-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520400859