Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function
Plasmacytoid dendritic cells (pDC) are an important regulator of immune responses. Here the authors show that pDC precursors, similar to peripheral blood-derived pDCs, can be differentiated from human CD34+ hematopoietic stem and progenitor cells, with type I/II IFN priming being required for their...
Full description
Bibliographic Details
| Main Authors: |
A. Laustsen,
R. O. Bak,
C. Krapp,
L. Kjær,
J. H. Egedahl,
C. C. Petersen,
S. Pillai,
H. Q. Tang,
N. Uldbjerg,
M. Porteus,
N. R. Roan,
M. Nyegaard,
P. W. Denton,
M. R. Jakobsen |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2018-08-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-018-05816-y
|
|---|
