Role of macrophage-mediated Toll-like receptor 4–interleukin-1R signaling in ectopic tongue pain associated with tooth pulp inflammation

Role of macrophage-mediated Toll-like receptor 4–interleukin-1R signaling in ectopic tongue pain associated with tooth pulp inflammation

Abstract Background The existence of referred pain and ectopic paresthesia caused by tooth pulp inflammation may make definitive diagnosis difficult and cause misdiagnosis or mistreatment; thus, elucidation of that molecular mechanism is urgent. In the present study, we investigated the mechanisms u...

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Bibliographic Details
Main Authors: Kohei Kanno, Kohei Shimizu, Masamichi Shinoda, Makoto Hayashi, Osamu Takeichi, Koichi Iwata
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Neuroinflammation
Subjects:
Intercellular signaling
Ectopic tongue pain
Toll-like receptors
Interleukin-1β
Transient receptor potential vanilloid 1
Cytokine receptors
Online Access:http://link.springer.com/article/10.1186/s12974-020-01995-y

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