Maltol Improves APAP-Induced Hepatotoxicity by Inhibiting Oxidative Stress and Inflammation Response via NF-κB and PI3K/Akt Signal Pathways

Maltol Improves APAP-Induced Hepatotoxicity by Inhibiting Oxidative Stress and Inflammation Response via NF-κB and PI3K/Akt Signal Pathways

Maltol, a food-flavoring agent and Maillard reaction product formed during the processing of red ginseng (<i>Panax ginseng</i>, C.A. Meyer), has been confirmed to exert a hepatoprotective effect in alcohol-induced oxidative damage in mice. However, its beneficial effects on acetaminophen...

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Bibliographic Details
Main Authors: Zi Wang, Weinan Hao, Junnan Hu, Xiaojie Mi, Ye Han, Shen Ren, Shuang Jiang, Yingping Wang, Xindian Li, Wei Li
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Antioxidants
Subjects:
maltol
acetaminophen
liver injury
oxidative stress
apoptosis
inflammation response
Online Access:https://www.mdpi.com/2076-3921/8/9/395

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