Optimal treatment of tuberous sclerosis complex associated renal angiomyolipomata: a systematic review

Renal angiomyolipomata associated with tuberous sclerosis complex are often bilateral, multiple and progressive. They cause significant morbidity and mortality in older children and adults. Surveillance and pre-emptive treatment reduce this risk. Recent research suggests treatment with mammalian tar...

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Bibliographic Details
Main Authors: John J. Bissler, John C. Kingswood
Format: Article
Language:English
Published: SAGE Publishing 2016-08-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287216641353
Description
Summary:Renal angiomyolipomata associated with tuberous sclerosis complex are often bilateral, multiple and progressive. They cause significant morbidity and mortality in older children and adults. Surveillance and pre-emptive treatment reduce this risk. Recent research suggests treatment with mammalian target of rapamycin inhibitors is better at preventing bleeding, recurrence, and preserving renal function than percutaneous embolization.
ISSN:1756-2872
1756-2880