Purβ promotes hepatic glucose production by increasing Adcy6 transcription

Objective: Enhanced glucagon signaling and hepatic glucose production (HGP) can account for hyperglycemia in patients with obesity and type 2 diabetes. However, the detailed molecular mechanisms underlying the enhanced HGP in these patients are not fully understood. Here, we identify Purβ as a posit...

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Bibliographic Details
Main Authors: Linna Jia, Yunfeng Jiang, Xinzhi Li, Zheng Chen
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819309408