A semi-quantitative assay of overall DNA methylation status using Methyl-CpG binding protein (MBD1)

<p>Abstract</p> <p>Background</p> <p>In mammals, DNA methylation at the 5-position of cytosine is the most essential epigenetic modification. Changes in the level of genome-wide DNA methylation (also known as overall DNA methylation) are associated with alterations in g...

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Bibliographic Details
Main Authors: Zhang Chunxiao, Li Runsheng, Zhao Ruqian
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Research Notes
Subjects:
Online Access:http://www.biomedcentral.com/1756-0500/5/234