Graphene quantum dots in alveolar macrophage: uptake-exocytosis, accumulation in nuclei, nuclear responses and DNA cleavage

Graphene quantum dots in alveolar macrophage: uptake-exocytosis, accumulation in nuclei, nuclear responses and DNA cleavage

Abstract Background Given the tremendous potential for graphene quantum dots (QDs) in biomedical applications, a thorough understanding of the interaction of these materials with macrophages is essential because macrophages are one of the most important barriers against exogenous particles. Although...

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Bibliographic Details
Main Authors: Lina Xu, Yanhui Dai, Zhenyu Wang, Jian Zhao, Fei Li, Jason C. White, Baoshan Xing
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Particle and Fibre Toxicology
Subjects:
Aminated graphene quantum dots
Macrophages
Endocytosis
Nuclear accumulation
DNA cleavage
Molecular docking
Online Access:http://link.springer.com/article/10.1186/s12989-018-0279-8

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