In silico identification of novel chemical compounds with antituberculosis activity for the inhibition of InhA and EthR proteins from Mycobacterium tuberculosis

Tuberculosis (TB) continuously poses a major public health concern around the globe, with a mounting death toll of approximately 1.4 million in 2019. Reduced bioavailability, elevated toxicity, increased side effects, and resistance of multiple first-line and second-line TB medications, including is...

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Bibliographic Details
Main Authors: Sajal Kumar Halder, Fatiha Elma
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405579421000358