A 38-gene model comprised of key TET2-associated genes shows additive utility to high-risk prostate cancer cases in the prognostication of biochemical recurrence

A 38-gene model comprised of key TET2-associated genes shows additive utility to high-risk prostate cancer cases in the prognostication of biochemical recurrence

Abstract Background Early treatment of patients at risk for developing aggressive prostate cancer is able to delay metastasis and reduce mortality; as such, up-front identification of these patients is critical. Several risk classification systems, including CAPRA-S, are currently used for disease p...

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Bibliographic Details
Main Authors: Shivani Kamdar, Neil E. Fleshner, Bharati Bapat
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
Prostate cancer
TET2
Gene expression
Statistical models
Biochemical recurrence
Online Access:http://link.springer.com/article/10.1186/s12885-020-07438-4

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