Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis

Srujan Kumar Gandham, Meghna Talekar, Amit Singh, Mansoor M Amiji Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA, USA Background: The objective of this study was to evaluate the expression levels of glycolytic markers, especially hexokinase-...

Full description

Bibliographic Details
Main Authors: Gandham SK, Talekar M, Singh A, Amiji MM
Format: Article
Language:English
Published: Dove Medical Press 2015-07-01
Series:International Journal of Nanomedicine
Online Access:http://www.dovepress.com/inhibition-of-hexokinase-2-with-targeted-liposomal-3-bromopyruvate-in--peer-reviewed-article-IJN