A tissue-engineered humanized xenograft model of human breast cancer metastasis to bone
The skeleton is a preferred homing site for breast cancer metastasis. To date, treatment options for patients with bone metastases are mostly palliative and the disease is still incurable. Indeed, key mechanisms involved in breast cancer osteotropism are still only partially understood due to the la...
Main Authors: | Laure Thibaudeau, Anna V. Taubenberger, Boris M. Holzapfel, Verena M. Quent, Tobias Fuehrmann, Parisa Hesami, Toby D. Brown, Paul D. Dalton, Carl A. Power, Brett G. Hollier, Dietmar W. Hutmacher |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-02-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/7/2/299 |
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