Serum free light chains and multiple myeloma: Is it time to extend their application?

Serum free light chains and multiple myeloma: Is it time to extend their application?

Abstract In nonsecretory, oligo‐secretory, and light chain multiple myeloma patients, serial sFLC evaluation could precede biochemical and clinical disease progression, even in extramedullary relapse, thus initiating early treatment with novel anti‐MM agents.

Bibliographic Details
Main Authors:	Uros Markovic, Valerio Leotta, Daniele Tibullo, Rachele Giubbolini, Alessandra Romano, Vittorio Del Fabro, Nunziatina Laura Parrinello, Maria Teresa Cannizzaro, Francesco Di Raimondo, Concetta Conticello
Format:	Article
Language:	English
Published:	Wiley 2020-04-01
Series:	Clinical Case Reports
Subjects:	disease progression extramedullary relapse multiple myeloma serological markers serum free light chains
Online Access:	https://doi.org/10.1002/ccr3.2636

Similar Items

A rare case of multiple myeloma with intracranial extramedullary relapse: One or more myeloma clones?
by: Uros Markovic, et al.
Published: (2019-09-01)

Carfilzomib Based Treatment Strategies in the Management of Relapsed/Refractory Multiple Myeloma with Extramedullary Disease
by: Xiang Zhou, et al.
Published: (2020-04-01)

Clinical Benefit of Long-Term Disease Control with Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma Patients
by: Marina Silvia Parisi, et al.
Published: (2019-10-01)

Extramedullary relapse of multiple myeloma defined as the highest risk group based on deregulated gene expression data
by: Sabina Sevcikova, et al.
Published: (2015-06-01)

Daratumumab as Single Agent in Relapsed/Refractory Myeloma Patients: A Retrospective Real-Life Survey
by: Uros Markovic, et al.
Published: (2021-03-01)

Mediastinal plasmocytoma with multiple myeloma: unusual presentation
by: Nouama Bouanani, et al.
Published: (2020-08-01)

Non-secretory multiple myeloma with extramedulary plasmocytoma
by: Abed Hussain Khan, et al.
Published: (2016-08-01)

Multiple myeloma with lung plasmacytoma
by: Rajendra Prasad, et al.
Published: (2011-01-01)

Multiple Extramedullary-Bone Related and/or Extramedullary Extraosseous Are Independent Poor Prognostic Factors in Patients With Newly Diagnosed Multiple Myeloma
by: JingSong He, et al.
Published: (2021-07-01)

Multiple myeloma presenting as CEA-producing rectal cancer
by: Giampaolo Talamo
Published: (2010-03-01)

Extramedullary Involvement of Lymph Nodes in Multiple Myeloma
by: Todorovic Zeljko, et al.
Published: (2017-10-01)

Multiple Myeloma with Hypoechoic Liver Nodules
by: Mathilde Duesberg, et al.
Published: (2019-10-01)

Large plasmacytoma occupying the upper limb in a myeloma patient
by: Junichiro Takano, et al.
Published: (2017-03-01)

Multiple myeloma masquerading as a pulmonary mass: A rare presentation
by: Mansi Kala, et al.
Published: (2012-03-01)

Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature
by: Munad Khan, et al.
Published: (2015-01-01)

Relapse of multiple myeloma presenting as extramedullary plasmacytoma surrounding the aorta: A rare case report
by: Omer Ekinci, et al.
Published: (2020-12-01)

Light Chain Escape Multiple Myeloma Complicated with Catastrophic Extramedullary Plasmacytoma Following Novel Agent Treatment
by: Yi-Ping Hung, et al.
Published: (2014-06-01)

Efficacy of Humanized Anti-BCMA CAR T Cell Therapy in Relapsed/Refractory Multiple Myeloma Patients With and Without Extramedullary Disease
by: Haobin Deng, et al.
Published: (2021-08-01)

Proptosis and hemiplegia as an initial manifestation of multiple myeloma
by: N Tahiliani, et al.
Published: (2018-01-01)

Pulmoner extramedullary hematopoiesis mimicking plasmacytoma in a patient with multiple myeloma candidate for autoHSCT
by: Serdar Sivgin
Published: (2014-08-01)

Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
by: Abhenil Mittal, et al.
Published: (2020-01-01)

Natural History and Prognostic Factors at First Relapse in Multiple Myeloma
by: Chen Wang, et al.
Published: (2020-07-01)

How we manage smoldering multiple myeloma
by: Alessandra Romano, et al.
Published: (2020-09-01)

Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells
by: Tibullo eDaniele, et al.
Published: (2015-10-01)

"Imaging features of extramedullary plasmacytoma of skull base with multiple myeloma"- a rare case
by: A Pancholi, et al.
Published: (2006-02-01)

Extramedullary Plasmacytoma of Soft Tissues and Gingiva
by: Amrit Kaur Kaler, et al.
Published: (2012-07-01)

Secondary extramedullary plasmacytoma of sigmoid colon in a patient with multiple myeloma: a case report
by: Dimitris Fagkrezos, et al.
Published: (2018-12-01)

Cutaneous involvement by multiple myeloma presenting as erythematous indurated plaques at the site of cardiac pacemaker insertion
by: Dean Jeremy Choong, MD, et al.
Published: (2021-06-01)

How I treat relapsed and/or refractory multiple myeloma
by: Hans C. Lee, et al.
Published: (2020-09-01)

A Case Report of Extramedullary Myeloma Mimicking Lymphoma with Extensive Abdominal Involvement
by: Jihae Moon, et al.
Published: (2019-09-01)

Patterns of relapse and outcome of elderly multiple myeloma patients treated as front-line therapy with novel agents combinations
by: Aurelio Lopez, et al.
Published: (2015-01-01)

Carfilzomib for relapsed and refractory multiple myeloma
by: Groen K, et al.
Published: (2019-04-01)

Bendamustine in patients with relapsed or refractory multiple myeloma
by: Michael M, et al.
Published: (2010-01-01)

Isolated Extramedullary Relapse of Acute Myelocytic Leukemia After Bone Marrow Transplantation Affecting Left Ventricle and Right Atrium in an Adult
by: LinYun Kong, et al.
Published: (2016-01-01)

Minimal Residual Disease Assessment Within the Bone Marrow of Multiple Myeloma: A Review of Caveats, Clinical Significance and Future Perspectives
by: Alessandra Romano, et al.
Published: (2019-08-01)

Recent Advances in the Treatment of Patients with Multiple Myeloma
by: Mario A. Legarda, et al.
Published: (2020-11-01)

Feasibility, Tolerability and Efficacy of Carfilzomib in Combination with Lenalidomide and Dexamethasone in Relapsed Refractory Myeloma Patients: A Retrospective Real-Life Survey of the Sicilian Myeloma Network
by: Concetta Conticello, et al.
Published: (2019-06-01)

Plasmacytoma of the mesentery
by: S M Thambi, et al.
Published: (2018-01-01)

Plasmacytoma in patients with multiple myeloma: morphology and immunohistochemistry
by: Maiia V. Firsova, et al.
Published: (2020-04-01)

Doxorubicin-Loaded PEG-CdTe Quantum Dots as a Smart Drug Delivery System for Extramedullary Multiple Myeloma Treatment
by: Dangui Chen, et al.
Published: (2018-11-01)