Serum free light chains and multiple myeloma: Is it time to extend their application?

Abstract In nonsecretory, oligo‐secretory, and light chain multiple myeloma patients, serial sFLC evaluation could precede biochemical and clinical disease progression, even in extramedullary relapse, thus initiating early treatment with novel anti‐MM agents.

Bibliographic Details
Main Authors: Uros Markovic, Valerio Leotta, Daniele Tibullo, Rachele Giubbolini, Alessandra Romano, Vittorio Del Fabro, Nunziatina Laura Parrinello, Maria Teresa Cannizzaro, Francesco Di Raimondo, Concetta Conticello
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.2636
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spelling doaj-657fa85075444633b56e89ba4c07bb882020-11-25T01:48:01ZengWileyClinical Case Reports2050-09042020-04-018461762410.1002/ccr3.2636Serum free light chains and multiple myeloma: Is it time to extend their application?Uros Markovic0Valerio Leotta1Daniele Tibullo2Rachele Giubbolini3Alessandra Romano4Vittorio Del Fabro5Nunziatina Laura Parrinello6Maria Teresa Cannizzaro7Francesco Di Raimondo8Concetta Conticello9UOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyUOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyDepartment of Biomedical and Biotechnological Sciences University of Catania Catania ItalyUOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyUOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyUOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyUOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyRadiology via Santa Sofia 78 AOU Policlinico‐"Vittorio Emanuele" Catania ItalyUOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyUOC di Ematologia con Trapianto di Midollo Osseo AOU "Policlinico‐Vittorio Emanuele” Catania ItalyAbstract In nonsecretory, oligo‐secretory, and light chain multiple myeloma patients, serial sFLC evaluation could precede biochemical and clinical disease progression, even in extramedullary relapse, thus initiating early treatment with novel anti‐MM agents.https://doi.org/10.1002/ccr3.2636disease progressionextramedullary relapsemultiple myelomaserological markersserum free light chains
collection DOAJ
language English
format Article
sources DOAJ
author Uros Markovic
Valerio Leotta
Daniele Tibullo
Rachele Giubbolini
Alessandra Romano
Vittorio Del Fabro
Nunziatina Laura Parrinello
Maria Teresa Cannizzaro
Francesco Di Raimondo
Concetta Conticello
spellingShingle Uros Markovic
Valerio Leotta
Daniele Tibullo
Rachele Giubbolini
Alessandra Romano
Vittorio Del Fabro
Nunziatina Laura Parrinello
Maria Teresa Cannizzaro
Francesco Di Raimondo
Concetta Conticello
Serum free light chains and multiple myeloma: Is it time to extend their application?
Clinical Case Reports
disease progression
extramedullary relapse
multiple myeloma
serological markers
serum free light chains
author_facet Uros Markovic
Valerio Leotta
Daniele Tibullo
Rachele Giubbolini
Alessandra Romano
Vittorio Del Fabro
Nunziatina Laura Parrinello
Maria Teresa Cannizzaro
Francesco Di Raimondo
Concetta Conticello
author_sort Uros Markovic
title Serum free light chains and multiple myeloma: Is it time to extend their application?
title_short Serum free light chains and multiple myeloma: Is it time to extend their application?
title_full Serum free light chains and multiple myeloma: Is it time to extend their application?
title_fullStr Serum free light chains and multiple myeloma: Is it time to extend their application?
title_full_unstemmed Serum free light chains and multiple myeloma: Is it time to extend their application?
title_sort serum free light chains and multiple myeloma: is it time to extend their application?
publisher Wiley
series Clinical Case Reports
issn 2050-0904
publishDate 2020-04-01
description Abstract In nonsecretory, oligo‐secretory, and light chain multiple myeloma patients, serial sFLC evaluation could precede biochemical and clinical disease progression, even in extramedullary relapse, thus initiating early treatment with novel anti‐MM agents.
topic disease progression
extramedullary relapse
multiple myeloma
serological markers
serum free light chains
url https://doi.org/10.1002/ccr3.2636
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