Discordant hepatic fatty acid oxidation and triglyceride hydrolysis leads to liver disease

To extract energy from stored lipids, fatty acids must first be liberated from triglyceride before their β-oxidation in mitochondria in a coordinated and stepwise manner. To determine the independent and interdependent roles of hepatic triglyceride hydrolysis and fatty acid oxidation, mice were gene...

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Bibliographic Details
Main Authors: Ebru S. Selen, Joseph Choi, Michael J. Wolfgang
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-01-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.135626