Discordant hepatic fatty acid oxidation and triglyceride hydrolysis leads to liver disease
To extract energy from stored lipids, fatty acids must first be liberated from triglyceride before their β-oxidation in mitochondria in a coordinated and stepwise manner. To determine the independent and interdependent roles of hepatic triglyceride hydrolysis and fatty acid oxidation, mice were gene...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2021-01-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.135626 |