Calcium binding-mediated sustained release of minocycline from hydrophilic multilayer coatings targeting infection and inflammation.

Calcium binding-mediated sustained release of minocycline from hydrophilic multilayer coatings targeting infection and inflammation.

Infection and inflammation are common complications that seriously affect the functionality and longevity of implanted medical implants. Systemic administration of antibiotics and anti-inflammatory drugs often cannot achieve sufficient local concentration to be effective, and elicits serious side ef...

Full description

Bibliographic Details
Main Authors: Zhiling Zhang, Camilla A Nix, Utku K Ercan, Jonathan A Gerstenhaber, Suresh G Joshi, Yinghui Zhong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3883660?pdf=render

Similar Items

Similar Items