α<sub>1</sub>-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro

α<sub>1</sub>-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro

Oxidative stress is associated with many renal disorders, both acute and chronic, and has also been described to contribute to the disease progression. Therefore, oxidative stress is a potential therapeutic target. The human antioxidant α<sub>1</sub>-microglobulin (A1M) is a plasma and t...

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Bibliographic Details
Main Authors: Amanda Kristiansson, Sara Davidsson, Maria E. Johansson, Sarah Piel, Eskil Elmér, Magnus J. Hansson, Bo Åkerström, Magnus Gram
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
α<sub>1</sub>-microglobulin
oxidative stress
human kidney epithelial cells
antioxidant defense
heme
mitochondrial respiration
Online Access:https://www.mdpi.com/1422-0067/21/16/5825

Internet

https://www.mdpi.com/1422-0067/21/16/5825

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