Immune Checkpoint Markers in Neuroendocrine Carcinoma of the Digestive System

Immune Checkpoint Markers in Neuroendocrine Carcinoma of the Digestive System

Digestive system neuroendocrine carcinomas (NECs) are rare neoplasms originating from neuroendocrine cells with a poor prognosis and limited effective treatments. Programmed cell death protein 1/ligand 1 (PD-1/PD-L1) blockade has been used in the management of more than 10 solid tumors and has achie...

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Bibliographic Details
Main Authors: Jiazhang Xing, Hongyan Ying, Ji Li, Yang Gao, Zhao Sun, Jiarui Li, Chunmei Bai, Yuejuan Cheng, Huanwen Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
immune cell infiltration
microsatellite instability
neuroendocrine carcinoma
programmed cell death ligand 1
tumor mutational burden
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00132/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00132/full

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