Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper

Oxidation of low density lipoprotein (LDL) in the artery wall leads to the formation of cholesterol oxidation products that may result in cytotoxicity. Different mechanisms could contribute to LDL oxidation in vivo resulting in characteristic and specific modification of the cholesterol molecule. Al...

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Bibliographic Details
Main Authors: R P Patel, U Diczfalusy, S Dzeletovic, M T Wilson, V M Darley-Usmar
Format: Article
Language:English
Published: Elsevier 1996-11-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752037485X