Myocardial hypertrophy overrides the angiogenic response to hypoxia.

Myocardial hypertrophy overrides the angiogenic response to hypoxia.

Cyanosis and myocardial hypertrophy frequently occur in combination. Hypoxia or cyanosis can be potent inducers of angiogenesis, regulating the expression of hypoxia-inducible factors (HIF), vascular endothelial growth factors (VEGF), and VEGF receptors (VEGFR-1 and 2); in contrast, pressure overloa...

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Bibliographic Details
Main Authors: Yeong-Hoon Choi, Douglas B Cowan, Meena Nathan, Dimitrios Poutias, Christof Stamm, Pedro J del Nido, Francis X McGowan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2603310?pdf=render

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http://europepmc.org/articles/PMC2603310?pdf=render

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