MTHFR 677C>T polymorphism and the risk of breast cancer: evidence from an original study and pooled data for 28031 cases and 31880 controls.

MTHFR 677C>T polymorphism and the risk of breast cancer: evidence from an original study and pooled data for 28031 cases and 31880 controls.

<h4>Background</h4>Methylenetetrahydrofolate reductase (MTHFR) acts at an important metabolic point in the regulation of cellular methylation reaction. It assists in the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. The latter aids in remethylation of homocys...

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Bibliographic Details
Main Authors: Singh Pooja, Justin Carlus, Deepa Sekhar, Amirtharaj Francis, Nishi Gupta, Rituraj Konwar, Sandeep Kumar, Surender Kumar, Kumarasamy Thangaraj, Singh Rajender
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0120654

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https://doi.org/10.1371/journal.pone.0120654

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