T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.

The chemokine CXCL12/SDF-1alpha interacts with its G-protein coupled receptor CXCR4 to induce migration of lymphoid and endothelial cells. T cell specific adapter protein (TSAd) has been found to promote migration of Jurkat T cells through interaction with the G protein beta subunit. However, the mo...

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Bibliographic Details
Main Authors: Tone Berge, Vibeke Sundvold-Gjerstad, Stine Granum, Thorny C B Andersen, Gunn B Holthe, Lena Claesson-Welsh, Amy H Andreotti, Marit Inngjerdingen, Anne Spurkland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2841202?pdf=render

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http://europepmc.org/articles/PMC2841202?pdf=render

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