Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses

Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses

<p>Abstract</p> <p>Background</p> <p>Hereditary Hemochromatosis (HH) is a genetic disease associated with iron overload, in which individuals homozygous for the mutant C282Y <it>HFE </it>associated allele are at risk for the development of a range of disorde...

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Bibliographic Details
Main Authors: Norris Suzanne, O'Dwyer Michael J, White Mary, Mankan Arun K, Lawless Matthew W
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/8/30

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