Intra-ovarian injection of platelet-rich plasma into ovarian tissue promoted rejuvenation in the rat model of premature ovarian insufficiency and restored ovulation rate via angiogenesis modulation

Intra-ovarian injection of platelet-rich plasma into ovarian tissue promoted rejuvenation in the rat model of premature ovarian insufficiency and restored ovulation rate via angiogenesis modulation

Abstract Premature Ovarian Insufficiency (POI) is viewed as a type of infertility in which the menopausal status occurs before the physiological age. Several therapeutic strategies have been introduced in clinic for POI treatment, although the outputs are not fully convincing. Platelet-rich plasma (...

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Bibliographic Details
Main Authors: Shahin Ahmadian, Sepideh Sheshpari, Mohammad Pazhang, Alberto Miranda Bedate, Rahim Beheshti, Mehran Mesgari Abbasi, Mohammad Nouri, Reza Rahbarghazi, Mahdi Mahdipour
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Reproductive Biology and Endocrinology
Subjects:
Platelet-rich plasma
Ovarian rejuvenation
Premature ovarian insufficiency
Angiogenesis
Fertility
Online Access:http://link.springer.com/article/10.1186/s12958-020-00638-4

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