Diabetes, pancreatic cancer, and metformin therapy

Diabetes, pancreatic cancer, and metformin therapy

Pancreatic cancer carries a poor prognosis as most patients present with advanced disease and preferred chemotherapy regimens offer only modest effects on survival. Risk factors include smoking, obesity, heavy alcohol, and chronic pancreatitis. Pancreatic cancer has a complex relationship with diabe...

Full description

Bibliographic Details
Main Authors: Jun eGong, Lori Allison Robbins, Aurelia eLugea, Richard T. Waldron, Christie Y. Jeon, Stephen J Pandol
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Physiology
Subjects:
Insulin
Metformin
diabetes
AMPK
Pancreatic Cancer
IGF-1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00426/full

Similar Items

Similar Items