Unexpected Rule-Changes in a Working Memory Task Shape the Firing of Histologically Identified Delay-Tuned Neurons in the Prefrontal Cortex

Summary: Working memory-guided behaviors require memory retention during delay periods, when subsets of prefrontal neurons have been reported to exhibit persistently elevated firing. What happens to delay activity when information stored in working memory is no longer relevant for guiding behavior?...

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Bibliographic Details
Main Authors: A. Tugrul Ozdemir, Michael Lagler, Sabria Lagoun, Hugo Malagon-Vina, Balint Lasztóczi, Thomas Klausberger
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471931767X