In silico analyses of CD14 molecule reveal significant evolutionary diversity, potentially associated with speciation and variable immune response in mammals
The cluster differentiation gene (CD14) is a family of monocyte differentiating genes that works in conjunction with lipopolysaccharide binding protein, forming a complex with TLR4 or LY96 to mediate innate immune response to pathogens. In this paper, we used different computational methods to eluci...
Main Authors: | Olanrewaju B. Morenikeji, Bolaji N. Thomas |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2019-07-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/7325.pdf |
Similar Items
-
The Role of the CD14 molecule in equine endotoxemia
by: Guedes Alves da Silva, Adriana
Published: (2017) -
The Alterations in CD14 Expression in Periodontitis: A Systematic Review
by: Vivian Hirsch, et al.
Published: (2021-03-01) -
SNP Diversity in <i>CD14</i> Gene Promoter Suggests Adaptation Footprints in Trypanosome Tolerant N’Dama (<i>Bos taurus</i>) but not in Susceptible White Fulani (<i>Bos indicus</i>) Cattle
by: Olanrewaju B. Morenikeji, et al.
Published: (2020-01-01) -
Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis
by: Michał Rudnik, et al.
Published: (2021-08-01) -
Ovine CD14- an Immune Response Gene Has a Role Against Gastrointestinal Nematode Haemonchus contortus—A Novel Report
by: Kavita Rawat, et al.
Published: (2021-07-01)