The combined effect of nuclear and mitochondrial genomes on the risk of developing multiple sclerosis

The combined effect of nuclear and mitochondrial genomes on the risk of developing multiple sclerosis

Multiple sclerosis (MS) is a severe chronic CNS disease characterized by autoimmune inflammation, demyelination, and neurodegeneration. The interaction of mitochondrial and nuclear genomes is shown to be important in the formation of a predisposition to many diseases.Objective: to analyze the associ...

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Bibliographic Details
Main Authors: M. S. Kozin, I. S. Kiselev, A. N. Boyko, O. G. Kulakova, O. O. Favorova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-08-01
Series:Nevrologiâ, Nejropsihiatriâ, Psihosomatika
Subjects:
multiple sclerosis
genetic polymorphism
mitochondrial genome
nuclear genome
association analysis
multilocus analysis
Online Access:https://nnp.ima-press.net/nnp/article/view/1396

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