Application of Digital Anti-Coincidence Counting Method for Primary Activity Determination of 59Fe

• Main Authors: A. Agusbudiman, K.B. Lee, J.M. Lee
• Format: Article
• Language: English
• Published: Center for Development of Nuclear Informatics, National Nuclear Energy Agency (BATAN) 2019-08-01
• Series: Atom Indonesia
• Subjects: 59fe standardization; anti- coincidence counting; liquid scintillation; digital coincidence counting; efficiency extrapolation method
• Online Access: http://aij.batan.go.id/index.php/aij/article/view/812

As a radiopharmaceutical, the use of 59Fe is classified as a high pharmaceutical risk product. Therefore, a standard reference for activity measurement of 59Fe is necessary to ensure its metrological aspect. This paper describes an alternative method for primary activity determination of 59Fe for establishing a standard reference. The 59Fe solution was prepared using two different cocktails and measured by the 4pb(LS)-g counting system using a digital anti-coincidence counting method with emulated live-time of the extending dead-time. A final activity results at the reference time for the two samples series are (473.32± 2.55) kBq/g and (477.14 ± 2.42) kBq/g with quoted uncertainty evaluated at k = 1. The final activity was compared to the value obtained from the other two coincidence counting method and found to be in a good agreement within its uncertainty value.