Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study

Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study

Colorectal cancer (CRC) recurrence is often attributable to circulating tumor cells and/or cancer stem cells (CSCs) that resist to conventional therapies and foster tumor progression. Isothiocyanates (ITCs) derived from Brassicaceae vegetables have demonstrated anticancer effects in CRC, however lit...

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Bibliographic Details
Main Authors: Lucília P. Pereira, Patrícia Silva, Marlene Duarte, Liliana Rodrigues, Catarina M. M. Duarte, Cristina Albuquerque, Ana Teresa Serra
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Nutrients
Subjects:
colorectal cancer
cancer stem cells
metastasis
phenethyl isothiocyanate
sulforaphane
Brassicaceae extracts
watercress
broccoli
Online Access:http://www.mdpi.com/2072-6643/9/4/368

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