Gaussian curvature and the budding kinetics of enveloped viruses.
The formation of a membrane-enveloped virus starts with the assembly of a curved layer of capsid proteins lining the interior of the plasma membrane (PM) of the host cell. This layer develops into a spherical shell (capsid) enveloped by a lipid-rich membrane. In many cases, the budding process stall...
Main Authors: | Sanjay Dharmavaram, Selene Baochen She, Guillermo Lázaro, Michael Francis Hagan, Robijn Bruinsma |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-08-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1006602 |
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